Hypocalcemia is a common complication after a total thyroidectomy. About 25% of the patients have low calcium levels in the blood serum after surgery. Resection of one or more parathyroid glands, but also ischemia (whether or not temporary) or edema around the operation site could cause postoperative hypocalcemia. Unfortunately, there is no evidence-based guideline for the treatment of this common problem. Treatment is usually based on the serum calcium and sometimes also the parathyroid hormone (PTH). However, recent studies suggest that in many cases this leads to overtreatment and that only treating patients who are symptomatic is more efficient and safe. In response to this finding, a treatment algorithm has been developed for Dutch practice based primarily on symptoms. The algorithm is expected to help optimize diagnostics and possibly prevent unnecessary treatment. This means that the number of blood tests and outpatient visits can be reduced and therefore also the burden on patients.
The purpose of this study is to investigate the effectiveness and safety of a new treatment algorithm for the treatment of hypocalcemia after a total thyroidectomy. This will be examined in a prospective multicenter trial conducted in ten hospitals in the Rotterdam region.
1. Elective total or totalization thyroidectomy.
2. Age ≥ 18 years
1. Preoperative abnormal corrected serum calcium (reference values 2.20 - 2.65 mmol/L)
3. History of epilepsy
5. Insufficient command of Dutch
6. Incapable of legal consent
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BackgroundThe treatment of hyperthyroidism caused by an autonomous thyroid nodule currently involves the use of radioactive I-131. A common complication of this therapy is the occu...
PurposeTo validate the prediction score that predicts the likelihood of requiring thyroid hormone supplementation after hemithyroidectomy. This score is based on the preoperative T...
Thyroid Network DatabaseThe Thyroid Network Database is a regional database, into which data has been entered retrospectively and is currently updated prospectively for all patient...